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Antibody concentrations decrease 14-fold in children with celiac disease on a gluten-free diet but remain high at 3 months

Abstract:
Background & Aims Celiac disease can be identified by a serologic test for IgA against tissue transglutaminase (IgA-TTG) in a large proportion of children. However, the increased concentrations of antibody rarely normalize within the months after children are placed on a gluten-free diet (GFD). Early serologic predictors of sufficient adherence to gluten-free diet are required for optimal treatment. Methods In a prospective study, we observed the respons... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.cgh.2018.04.008

Authors


Petroff, D More by this author
Richter, T More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; NDM Experimental Medicine
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Publisher:
AGA Institute Publisher's website
Journal:
Clinical Gastroenterology and Hepatology Journal website
Volume:
16
Issue:
9
Pages:
1442-1449.e5
Publication date:
2018-04-12
DOI:
EISSN:
1542-7714
ISSN:
1542-3565
Pubs id:
pubs:844413
URN:
uri:5718153d-3d31-419c-8dc4-506909ee4eed
UUID:
uuid:5718153d-3d31-419c-8dc4-506909ee4eed
Local pid:
pubs:844413

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