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Factor I autoantibodies in patients with atypical hemolytic uremic syndrome: disease-associated or an epiphenomenon?

Abstract:

BACKGROUND AND OBJECTIVES: Atypical hemolytic uremic syndrome is a disease associated with mutations in the genes encoding the complement regulators factors H and I. In addition, factor H autoantibodies have been reported in ∼10% of patients with atypical hemolytic uremic syndrome. This study searched for the presence of factor I autoantibodies in atypical hemolytic uremic syndrome. DESIGN, SETTING, PARTICIPANTS, and MEASUREMENTS: This study screened 175 atypical hemolytic uremic syndrome pa...

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Publication status:
Published

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Publisher copy:
10.2215/CJN.05750611

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Journal:
Clinical journal of the American Society of Nephrology : CJASN
Volume:
7
Issue:
3
Pages:
417-426
Publication date:
2012-03-05
DOI:
EISSN:
1555-905X
ISSN:
1555-9041
URN:
uuid:570f85e0-5cc3-47c4-8200-3b68b4e51a9e
Source identifiers:
237716
Local pid:
pubs:237716

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