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Journal article

Peripheral blood invariant natural killer T cells throughout pregnancy and in preeclamptic women.

Abstract:

Invariant natural killer T (iNKT) cells are implicated in the pathogenesis of several diseases. They influence both innate and adaptive immune responses through their capacity to rapidly produce large quantities of cytokines upon activation. During pregnancy maternal immunity is biased towards type 2 cytokine production to regulate type 1 cytokines that could be harmful for the developing fetus. This shift to type 2 cytokines does not occur in preeclamptic women and there is an exaggerated ma...

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Publication status:
Published

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Publisher copy:
10.1016/j.jri.2010.07.003

Authors


Southcombe, J More by this author
Sargent, I More by this author
Journal:
Journal of reproductive immunology
Volume:
87
Issue:
1-2
Pages:
52-59
Publication date:
2010-12-05
DOI:
EISSN:
1872-7603
ISSN:
0165-0378
URN:
uuid:56e6faf7-f259-4886-996b-bf95c17387a7
Source identifiers:
314640
Local pid:
pubs:314640

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