- Abstract:
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PURPOSE: Hypothalamic GABA signaling has been shown to regulate the hormonal response to hypoglycemia in animals. The hypothalamus is a challenging brain region for magnetic resonance spectroscopy (MRS) due to its small size and central location. To investigate the feasibility of measuring GABA in the hypothalamus in humans, ultra-high field MRS was used. METHODS: GABA levels in the hypothalamus and occipital cortex (control region) were measured in healthy volunteers during euglycemia and hy...
Expand abstract - Publisher copy:
- 10.1002/mrm.24663
-
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- Journal:
- Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine
- Volume:
- 71
- Issue:
- 1
- Pages:
- 12-18
- Publication date:
- 2014-01-05
- DOI:
- EISSN:
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1522-2594
- ISSN:
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0740-3194
- URN:
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uuid:56db70f6-5260-423d-ba7a-7e4d72d01f62
- Source identifiers:
-
457580
- Local pid:
- pubs:457580
- Copyright date:
- 2014
Journal article
Initial experience with seven tesla magnetic resonance spectroscopy of hypothalamic GABA during hyperinsulinemic euglycemia and hypoglycemia in healthy humans.
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