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The C/EBP family of transcription factors: a paradigm for interaction between gene expression and proliferation control.

Abstract:

In recent years, a link between the transcriptional regulators of lineage-specific gene expression and progenitor proliferation control has emerged. A main exponent of this phenomenon is the CCAAT/enhancer binding protein (C/EBP) family of basic region-leucine zipper proteins. These transcription factors control the differentiation of a range of cell types, and have key roles in regulating cellular proliferation through interaction with cell cycle proteins. More recently, their position at th...

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Publisher copy:
10.1016/j.tcb.2007.07.004

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Clinical Lab Sciences, Molecular Medicine
Role:
Author
Journal:
Trends in cell biology
Volume:
17
Issue:
7
Pages:
318-324
Publication date:
2007-07-05
DOI:
EISSN:
1879-3088
ISSN:
0962-8924
URN:
uuid:56bec9dc-3795-4177-8b16-b6d0df83ea54
Source identifiers:
324061
Local pid:
pubs:324061

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