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Monte Carlo dose calculations and radiobiological modelling: analysis of the effect of the statistical noise of the dose distribution on the probability of tumour control.

Abstract:

The aim of this work is to investigate the influence of the statistical fluctuations of Monte Carlo (MC) dose distributions on the dose volume histograms (DVHs) and radiobiological models, in particular the Poisson model for tumour control probability (tcp). The MC matrix is characterized by a mean dose in each scoring voxel, d, and a statistical error on the mean dose, sigma(d); whilst the quantities d and sigma(d) depend on many statistical and physical parameters, here we consider only the...

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Publisher copy:
10.1088/0031-9155/45/10/318

Authors


Journal:
Physics in medicine and biology
Volume:
45
Issue:
10
Pages:
3009-3023
Publication date:
2000-10-05
DOI:
EISSN:
1361-6560
ISSN:
0031-9155
URN:
uuid:56be9aea-c77c-48d7-988d-7e7cb66d1f25
Source identifiers:
274345
Local pid:
pubs:274345

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