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Maintenance of clinical remission in ANCA-associated vasculitis.

Abstract:

A fundamental change in management of antineutrophil cytoplasmic antibody-associated vasculitis in the past 10 years is the early focussed use of aggressive immunosuppression, using regimens comprised of widely available medications. Using a clinical framework to quantify morbidity, we can induce remission in most patients within 3-6 months using glucocorticoids plus methotrexate, cyclophosphamide or rituximab, with additional plasmapheresis when indicated. Difficulty in maintaining remission...

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Publication status:
Published

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Publisher copy:
10.1038/nrrheum.2012.188

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Journal:
Nature reviews. Rheumatology
Volume:
9
Issue:
2
Pages:
127-132
Publication date:
2013-02-05
DOI:
EISSN:
1759-4804
ISSN:
1759-4790
URN:
uuid:56b05340-b11d-41f5-8680-618062de6cb5
Source identifiers:
363836
Local pid:
pubs:363836

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