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Predicted phenotypes of dry eye - proposed consequences of its natural history

Abstract:

This paper reviews current knowledge of the pathophysiology of dry eye and predicts that the clinical picture in late disease differs in both severity and quality from that in early disease. It is hypothesized that hybrid forms evolve, in which aqueous-deficient dry eye (ADDE) takes on features of evaporative dry eye (EDE) and vice versa. As a consequence, early and late forms may require different diagnostic criteria and respond to different therapeutic regimes. Tear hyperosmolarity plays a ...

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E. A. Gaffney More by this author
J M Tiffany More by this author
Publication date:
2009
URN:
uuid:5695fadd-0b52-4329-9a20-d24197810bbd
Local pid:
oai:eprints.maths.ox.ac.uk:887

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