Journal article icon

Journal article

Single cell analysis of normal and leukemic hematopoiesis

Abstract:

The hematopoietic system is well established as a paradigm for the study of cellular hierarchies, their disruption in disease and therapeutic use in regenerative medicine. Traditional approaches to study hematopoiesis involve purification of cell populations based on a small number of surface markers. However, such population-based analysis obscures underlying heterogeneity contained within any phenotypically defined cell population. This heterogeneity can only be resolved through single cell...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

Actions


Access Document


Files:
Publisher copy:
10.1016/j.mam.2017.08.006

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Weatherall Insti. of Molecular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Weatherall Insti. of Molecular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Weatherall Insti. of Molecular Medicine
Role:
Author
More from this funder
Grant:
(MR/L006340/1) (MC_UU_12009/5) (MR/M00919X/1)
Publisher:
Elsevier Publisher's website
Journal:
Molecular Aspects of Medicine Journal website
Volume:
59
Pages:
85-94
Publication date:
2017-08-29
Acceptance date:
2017-08-28
DOI:
EISSN:
1872-9452
ISSN:
0098-2997
Pubs id:
pubs:726010
URN:
uri:568d3774-3e32-45c5-9e18-b337cab74761
UUID:
uuid:568d3774-3e32-45c5-9e18-b337cab74761
Local pid:
pubs:726010

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP