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Journal article

Plasmodium falciparum intercellular adhesion molecule-1-based cytoadherence-related signaling in human endothelial cells.

Abstract:

BACKGROUND: Cytoadherence of Plasmodium falciparum-infected erythrocytes to host endothelium has been associated with pathology in severe malaria, but, despite extensive information on the primary processes involved in the adhesive interactions, the mechanisms underlying disease are poorly understood. METHODS: We compared parasite lines varying in their binding properties to human endothelial cells for their ability to stimulate signaling activity. RESULTS: In human umbilical vein endothelial...

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Publication status:
Published

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Publisher copy:
10.1086/518795

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Role:
Author
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Journal:
The Journal of infectious diseases
Volume:
196
Issue:
2
Pages:
321-327
Publication date:
2007-07-05
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
URN:
uuid:567dc46d-ad8b-4ae3-a6f4-ea359d25d8d6
Source identifiers:
140099
Local pid:
pubs:140099

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