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Natriuretic peptide guided therapy for management of patients with heart failure does not show improvement compared with usual medical therapy alone

Abstract:

Natriuretic peptides (NPs), a collective term for B-type natriuretic peptide (BNP) and N (or amino)-terminal pro-B-type natriuretic peptide (NT-proBNP), are released by the myocardium in response to pressure or fluid overload. In patients with heart failure (HF) the NP levels are raised. NP testing is currently used in diagnosis and prognosis, but its role in guiding HF treatment remains uncertain. The guidelines do not currently recommend NP guided treatment. Previous clinical trials and ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1136/bmjebm-2017-110880

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Primary Care; Primary Care Health Sciences
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Primary Care; Primary Care Health Sciences
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Grant:
Programme Grants for Applied Research Programme (Reference Number RP-PG-1210-12003)
Publisher:
BMJ Publishing Group Publisher's website
Journal:
BMJ Evidence-Based Medicine Journal website
Volume:
23
Issue:
2
Pages:
74-75
Publication date:
2018-02-22
Acceptance date:
2018-01-19
DOI:
EISSN:
1473-6810
ISSN:
1356-5524
Pubs id:
pubs:820970
URN:
uri:56764c3f-40d1-4511-a2d1-d6276db3fa88
UUID:
uuid:56764c3f-40d1-4511-a2d1-d6276db3fa88
Local pid:
pubs:820970

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