Journal article icon

Journal article

pH-Dependence of extrinsic and intrinsic H(+)-ion mobility in the rat ventricular myocyte, investigated using flash photolysis of a caged-H(+) compound.

Abstract:

Passive H(+)-ion mobility within eukaryotic cells is low, due to H(+)-ion binding to cytoplasmic buffers. A localized intracellular acidosis can therefore persist for seconds or even minutes. Because H(+)-ions modulate so many biological processes, spatial intracellular pH (pH(i))-regulation becomes important for coordinating cellular activity. We have investigated spatial pH(i)-regulation in single and paired ventricular myocytes from rat heart by inducing a localized intracellular acid-load...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1529/biophysj.106.096560

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Biophysical journal
Volume:
92
Issue:
2
Pages:
641-653
Publication date:
2007-01-01
DOI:
EISSN:
1542-0086
ISSN:
0006-3495
Source identifiers:
106467
Language:
English
Keywords:
Pubs id:
pubs:106467
UUID:
uuid:56756164-1671-41b9-89c3-5921eba0f461
Local pid:
pubs:106467
Deposit date:
2013-11-17

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP