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Thesis

Design of a defocused transducer for targeted cancer drug delivery by ultrasound-mediated hyperthermia

Abstract:

A major challenge in chemotherapy is that the systemic delivery of drugs to both healthy tissue as well as the tumour results in unwanted side effects. Thermosensitive liposomal carriers are designed to release their payload when they are exposed to mild hyperthermia (a few degrees above body temperature). If a tumour can be locally heated, thermosensitive liposomes can provide triggered and localised delivery of the drug which should reduce systemic toxicity. Ultrasound is a noninvasive ...

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Division:
MSD
Department:
University of Oxford
Role:
Author

Contributors

Department:
University of Oxford
Role:
Supervisor
Department:
University of Oxford
Role:
Supervisor
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Grant:
EP/G036861/1
Funding agency for:
Chu, BTC
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:567466c1-c871-4493-a787-ca5a19c3f9f2
Language:
English
Keywords:
Subjects:

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