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LuxS: its role in central metabolism and the in vitro synthesis of 4-hydroxy-5-methyl-3(2H)-furanone.

Abstract:

Many bacteria produce extracellular molecules which function in cell-to-cell communication. One of these molecules, autoinducer 2 (AI-2), was first described as an extracellular signal produced by Vibrio harveyi to control luciferase expression. Subsequently, a number of bacteria have been shown to possess AI-2 activity in their culture supernatants, and bear the luxS gene product, which is required for AI-2 synthesis. In Porphyromonas gingivalis, luxS and pfs, encoding a 5'-methylthioadenosi...

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Publication status:
Published

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Journal:
Microbiology (Reading, England)
Volume:
148
Issue:
Pt 4
Pages:
909-922
Publication date:
2002-04-05
EISSN:
1465-2080
ISSN:
1350-0872
URN:
uuid:56658888-d276-4b75-9f40-72db28be8714
Source identifiers:
377304
Local pid:
pubs:377304

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