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Neuropeptide-Y stimulates CRF-41 release from rat hypothalami in vitro.

Abstract:

There is increasing evidence that neuropeptide-Y (NPY) exerts a stimulatory effect on the hypothalamo-pituitary-adrenal axis. Although it has been suggested that this stimulatory effect may be mediated via an action on hypothalamic CRF-41 release, direct measurements have not previously been made. In this study, the direct effect of NPY on hypothalamic CRF-41 secretion has been investigated in vitro using acute hypothalamic explants and previously described incubation techniques. NPY in the c...

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Publication status:
Published

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Authors


Tsagarakis, S More by this author
Besser, GM More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Journal:
Brain research
Volume:
502
Issue:
1
Pages:
167-170
Publication date:
1989-11-05
DOI:
EISSN:
1872-6240
ISSN:
0006-8993
URN:
uuid:5662c7c6-ca5a-4345-ac4f-f143dfb3de29
Source identifiers:
138137
Local pid:
pubs:138137

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