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Ursodeoxycholic acid versus placebo in the treatment of women with intrahepatic cholestasis of pregnancy (ICP) to improve perinatal outcomes: protocol for a randomised controlled trial (PITCHES)

Abstract:

Background: Intrahepatic cholestasis of pregnancy (ICP) is the most common liver disorder specific to pregnancy and presents with maternal pruritus, raised concentrations of serum bile acids and abnormal liver function tests. ICP is associated with increased rates of spontaneous and iatrogenic preterm labou...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/s13063-018-3018-4

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Role:
Author
ORCID:
0000-0001-6219-3379
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King’s College London More from this funder
Guy’s and St Thomas’ NHS Foundation Trust More from this funder
Publisher:
BMC Publisher's website
Journal:
Trials Journal website
Volume:
19
Pages:
Article: 657
Publication date:
2018-11-27
Acceptance date:
2018-10-24
DOI:
EISSN:
1745-6215
Pubs id:
pubs:948835
URN:
uri:5644c15d-479b-40c8-bfcf-52d92c9503db
UUID:
uuid:5644c15d-479b-40c8-bfcf-52d92c9503db
Local pid:
pubs:948835

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