- Abstract:
-
Many studies on the role of merozoite surface protein 3 (MSP3) in immunity against malaria have focused on a conserved section of MSP3. New evidence suggests that polymorphic sequences within MSP3 are under immune selection. We report a detailed analysis of naturally-acquired antibodies to allele-specific and conserved parts of MSP3 in a Kenyan cohort. Indirect and competition ELISA to heterologous recombinant MSP3 proteins were used for antibody assays, and parasites were genotyped for msp3 ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1111/j.1365-3024.2007.00951.x
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- Journal:
- Parasite immunology
- Volume:
- 29
- Issue:
- 8
- Pages:
- 387-394
- Publication date:
- 2007-08-05
- DOI:
- EISSN:
-
1365-3024
- ISSN:
-
0141-9838
- URN:
-
uuid:561bd9c7-11e9-467d-a220-8ddd2e333f3b
- Source identifiers:
-
140095
- Local pid:
- pubs:140095
- Copyright date:
- 2007
Journal article
Naturally acquired antibodies to polymorphic and conserved epitopes of Plasmodium falciparum merozoite surface protein 3.
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