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Transforming clinical microbiology with bacterial genome sequencing.

Abstract:

Whole-genome sequencing of bacteria has recently emerged as a cost-effective and convenient approach for addressing many microbiological questions. Here, we review the current status of clinical microbiology and how it has already begun to be transformed by using next-generation sequencing. We focus on three essential tasks: identifying the species of an isolate, testing its properties, such as resistance to antibiotics and virulence, and monitoring the emergence and spread of bacterial patho...

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Publication status:
Published

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Publisher copy:
10.1038/nrg3226

Authors


Didelot, X More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Journal:
Nature reviews. Genetics
Volume:
13
Issue:
9
Pages:
601-612
Publication date:
2012-09-05
DOI:
EISSN:
1471-0064
ISSN:
1471-0056
URN:
uuid:56199ce8-38fe-4189-8b89-842642dec22b
Source identifiers:
345624
Local pid:
pubs:345624

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