Journal article
The Fidelity of Synaptonemal Complex Assembly Is Regulated by a Signaling Mechanism that Controls Early Meiotic Progression
- Abstract:
-
Proper chromosome segregation during meiosis requires the assembly of the synaptonemal complex (SC) between homologous chromosomes. However, the SC structure itself is indifferent to homology, and poorly understood mechanisms that depend on conserved HORMA-domain proteins prevent ectopic SC assembly. Although HORMA-domain proteins are thought to regulate SC assembly as intrinsic components of meiotic chromosomes, here we uncover a key role for nuclear soluble HORMA-domain protein HTP-1 in the...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1016/j.devcel.2014.10.001
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Authors
Funding
Bibliographic Details
- Publisher:
- Cell Press Publisher's website
- Journal:
- Developmental Cell Journal website
- Volume:
- 31
- Issue:
- 4
- Pages:
- 503-511
- Publication date:
- 2014-11-06
- Acceptance date:
- 2014-09-30
- DOI:
- EISSN:
-
1878-1551
- ISSN:
-
1534-5807
- Pmid:
-
25455309
- Source identifiers:
-
502218
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:502218
- UUID:
-
uuid:560e8dac-e5e4-4475-9546-38fb4fec7857
- Local pid:
- pubs:502218
- Deposit date:
- 2019-07-02
Terms of use
- Copyright holder:
- Elsevier
- Copyright date:
- 2014
- Notes:
- © 2014 Elsevier Inc.
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