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Investigation of susceptibility loci identified in the UK rheumatoid arthritis whole-genome scan in a further series of 217 UK affected sibling pairs.

Abstract:

OBJECTIVE: A previous whole-genome scan (WGS) of 182 UK rheumatoid arthritis (RA) affected sibling pair (ASP) families suggested linkage to HLA and 11 other chromosome regions. Replication of such findings in an independent cohort can help to distinguish true linkages from false-positive linkages. Since RA is a heterogeneous disease, some loci may be linked only in subsets of patients. Thus, the aim of this study was to investigate in an additional set of RA ASP families linkage to regions s...

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Publication status:
Published

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Publisher copy:
10.1002/art.20039

Authors


Shephard, N More by this author
Brintnell, W More by this author
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Journal:
Arthritis and rheumatism
Volume:
50
Issue:
3
Pages:
729-735
Publication date:
2004-03-05
DOI:
EISSN:
1529-0131
ISSN:
0004-3591
URN:
uuid:55d79334-46fd-41d4-966a-5118862b6a8f
Source identifiers:
108326
Local pid:
pubs:108326

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