- Abstract:
-
Estrogen is essential for the development and maintenance of optimal bone mass in women and men, and acts through activation of estrogen receptors (ER). We have examined the pathways of estrogen action on the skeleton by seeking to localize the "classical" estrogen receptor, ER alpha, to particular cells to test the hypotheses that 1) estrogen directly influences growth plate chondrocytes; and 2) estrogen has a principal action on bone tissue via osteoblasts. ER alpha messenger ribonucleic ac...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1210/jc.83.7.2421
-
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- Journal:
- The Journal of clinical endocrinology and metabolism
- Volume:
- 83
- Issue:
- 7
- Pages:
- 2421-2428
- Publication date:
- 1998-07-05
- DOI:
- EISSN:
-
1945-7197
- ISSN:
-
0021-972X
- URN:
-
uuid:55c276cb-dd23-4c47-b032-94e979870baf
- Source identifiers:
-
108319
- Local pid:
- pubs:108319
- Copyright date:
- 1998
Journal article
Localization of estrogen receptor-alpha in human and rabbit skeletal tissues.
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