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Journal article

Dual transcriptome of the immediate neutrophil and Candida albicans interplay.

Abstract:

Background

Neutrophils are traditionally considered transcriptionally inactive. Compared to other immune cells, little is known about their transcriptional profile during interaction with pathogens.

Methods

We analyzed the meta-transcriptome of the neutrophil-Candida albicans interplay and the transcriptome of C. albicans challenged with neutrophil extracellular traps (NETs) by RNA-Seq, considering yeast and hypha individually in each approach.

Results

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Files:
Publisher copy:
10.1186/s12864-017-4097-4

Authors


Niemiec, MJ More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM; Weatherall Insti. of Molecular Medicine
Shankar, M More by this author
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Swedish Research Council More from this funder
Umeå University More from this funder
Laboratory for Molecular Infection medicine Sweden More from this funder
Åke Wiberg Foundation More from this funder
Kempe Foundation More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
BMC Genomics Journal website
Volume:
18
Issue:
1
Pages:
696
Publication date:
2017-09-05
Acceptance date:
2017-08-30
DOI:
EISSN:
1471-2164
ISSN:
1471-2164
Pubs id:
pubs:729267
URN:
uri:55b59f7a-4aa3-4e50-a92c-ba37893573ec
UUID:
uuid:55b59f7a-4aa3-4e50-a92c-ba37893573ec
Local pid:
pubs:729267

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