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Journal article

Crystallization and preliminary X-ray analysis of the human respiratory syncytial virus nucleocapsid protein.

Abstract:

Human respiratory syncytial virus (HRSV) has a nonsegmented negative-stranded RNA genome which is encapsidated by the HRSV nucleocapsid protein (HRSVN) that is essential for viral replication. HRSV is a common cause of respiratory infection in infants, yet no effective antiviral drugs to combat it are available. Recent data from an experimental anti-HRSV compound, RSV-604, indicate that HRSVN could be the target site for drug action. Here, the expression, purification and preliminary data col...

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Publication status:
Published

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Publisher copy:
10.1107/s1744309108031059

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Journal:
Acta crystallographica. Section F, Structural biology and crystallization communications
Volume:
64
Issue:
Pt 11
Pages:
1019-1023
Publication date:
2008-11-01
DOI:
EISSN:
1744-3091
ISSN:
1744-3091
Source identifiers:
72654
Language:
English
Keywords:
Pubs id:
pubs:72654
UUID:
uuid:55ae7ab8-77b2-4710-9df9-f30afe71fee3
Local pid:
pubs:72654
Deposit date:
2012-12-19

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