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Symptomatic relapse in bulimia nervosa following acute tryptophan depletion.

Abstract:

BACKGROUND: Preclinical and clinical studies suggest that lowered brain serotonin neurotransmission may contribute to the pathophysiology of bulimia nervosa (BN). The aim of our study was to test this hypothesis by examining the psychological effects of a dietary-induced impairment in serotonin activity in subjects known to be at risk for manifestation of the clinical syndrome of BN. METHODS: An 85.8 g amino acid mixture lacking the serotonin precursor tryptophan and a balanced mixture were a...

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Publication status:
Published

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Publisher copy:
10.1001/archpsyc.56.2.171

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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Role:
Author
Journal:
Archives of general psychiatry
Volume:
56
Issue:
2
Pages:
171-176
Publication date:
1999-02-05
DOI:
EISSN:
1538-3636
ISSN:
0003-990X
URN:
uuid:55a7c0ed-5329-4317-94a3-732fbc33d8a0
Source identifiers:
185760
Local pid:
pubs:185760

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