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Journal article

Isolation and characterization of murine Cds (CDP-diacylglycerol synthase) 1 and 2.

Abstract:

Phototransduction in Drosophila is a phosphoinositide-mediated signalling pathway. Phosphatidylinositol 4,5-bisphosphate (PIP2) plays a central role in this process, and its levels are tightly regulated. A photoreceptor-specific form of the enzyme CDP-diacylglycerol synthase (CDS), which catalyzes the formation of CDP-diacylglycerol from phosphatidic acid, is a key regulator of the amount of PIP2 available for signalling. cds mutants develop light-induced retinal degeneration. We report here ...

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Publication status:
Published

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Publisher copy:
10.1016/j.gene.2005.04.037

Authors


Inglis-Broadgate, SL More by this author
Banerjee, R More by this author
Gaasenbeek, M More by this author
Chapple, JP More by this author
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Journal:
Gene
Volume:
356
Issue:
1-2
Pages:
19-31
Publication date:
2005-08-05
DOI:
EISSN:
1879-0038
ISSN:
0378-1119
URN:
uuid:555191a8-0139-45ca-8736-047b1990bea4
Source identifiers:
251613
Local pid:
pubs:251613

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