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Impact of atorvastatin and omega-3 ethyl esters 90 on plasma plant sterol concentrations and cholesterol synthesis in type 2 diabetes: a randomised placebo controlled factorial trial.

Abstract:

OBJECTIVE: To determine the effects of statin treatment and omega-3 polyunsaturated fatty acid supplementation on plasma plant sterol concentrations and cholesterol synthesis in patients with type 2 diabetes. METHODS: Plant sterol concentrations and lanosterol (a marker of cholesterol synthesis) were measured using a high sensitivity assay to assess the effect of double-blind daily treatment for 4 months with atorvastatin 20mg or placebo and, in a 2 × 2 factorial design, omega-3 ethyl esters...

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Publication status:
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Institution:
University of Oxford
Department:
Oxford
Ceglarek, U More by this author
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Journal:
Atherosclerosis
Volume:
213
Issue:
2
Pages:
512-517
Publication date:
2010-12-05
DOI:
EISSN:
1879-1484
ISSN:
0021-9150
URN:
uuid:553ed7ed-9838-49c0-b31e-201cb94a56d2
Source identifiers:
93173
Local pid:
pubs:93173

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