Oxygen and lactate concentrations measured in vivo in the intervertebral discs of patients with scoliosis and back pain.
STUDY DESIGN: Oxygen concentrations in intervertebral discs were measured in 10 patients during discography and in 13 patients with scoliosis and 11 patients with back pain during spinal surgery. Lactate concentration profiles were measured in 12 of these discs. The discs were graded for degeneration by magnetic resonance imaging and histology where possible. OBJECTIVES: To determine if oxygen and lactate levels in human discs vary with degree of degeneration. Failure of nutrient transport is...Expand abstract
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