Journal article
Virus-induced immunosuppression. 1. Age at infection relates to a selective or generalized defect.
- Abstract:
-
Viruses that persist must develop strategies to escape immunologic surveillance in order to survive. Investigation of lymphocytic choriomeningitis virus (LCMV)-induced persistence has indicated that this virus avoids immune clearance mainly by aborting the viral specific cytotoxic T lymphocyte (CTL) response, a response that is necessary for terminating viral infection. This study demonstrates that persistence established in immunologically immature newborns selectively depletes the LCMV-spec...
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- Publication status:
- Published
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- Publisher copy:
- 10.1006/viro.1993.1389
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Authors
Bibliographic Details
- Journal:
- Virology
- Volume:
- 195
- Issue:
- 2
- Pages:
- 397-405
- Publication date:
- 1993-08-01
- DOI:
- EISSN:
-
1096-0341
- ISSN:
-
0042-6822
- Source identifiers:
-
35852
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:35852
- UUID:
-
uuid:551bb25e-9094-4e41-bc89-addc22c0581f
- Local pid:
- pubs:35852
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 1993
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