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Is inhibition of the renin-angiotensin system a new treatment option for Alzheimer's disease?

Abstract:

Findings from longitudinal and cross-sectional studies suggest an association between high blood pressure and dementia, and in turn the use of antihypertensives has been suggested to reduce incidence of dementia. Alzheimer's disease, the most common cause of dementia, is characterised in part by the deposition of amyloid beta protein (Abeta) in the brain. Reduction of Abeta load is now a major therapeutic strategy. In recent years the renin-angiotensin system, already of recognised importance...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Lancet. Neurology
Volume:
6
Issue:
4
Pages:
373-378
Publication date:
2007-04-01
DOI:
EISSN:
1474-4465
ISSN:
1474-4422
Source identifiers:
33787
Language:
English
Keywords:
Pubs id:
pubs:33787
UUID:
uuid:551a142e-b7fc-47d5-ac1e-2714e3f2b8ff
Local pid:
pubs:33787
Deposit date:
2012-12-19

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