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Journal article

Cell-surface central nervous system autoantibodies: clinical relevance and emerging paradigms.

Abstract:

The recent discovery of several potentially pathogenic autoantibodies has helped identify patients with clinically distinctive central nervous system diseases that appear to benefit from immunotherapy. The associated autoantibodies are directed against the extracellular domains of cell-surface-expressed neuronal or glial proteins such as LGI1, N-methyl-D-aspartate receptor, and aquaporin-4. The original descriptions of the associated clinical syndromes were phenotypically well circumscribed. ...

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Publication status:
Published

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Publisher copy:
10.1002/ana.24200

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
Journal:
Annals of neurology
Volume:
76
Issue:
2
Pages:
168-184
Publication date:
2014-08-05
DOI:
EISSN:
1531-8249
ISSN:
0364-5134
URN:
uuid:550792b9-46b7-411f-afe6-5b6a458816dc
Source identifiers:
470416
Local pid:
pubs:470416
Language:
English

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