Journal article icon

Journal article

Cell-surface central nervous system autoantibodies: clinical relevance and emerging paradigms.

Abstract:

The recent discovery of several potentially pathogenic autoantibodies has helped identify patients with clinically distinctive central nervous system diseases that appear to benefit from immunotherapy. The associated autoantibodies are directed against the extracellular domains of cell-surface-expressed neuronal or glial proteins such as LGI1, N-methyl-D-aspartate receptor, and aquaporin-4. The original descriptions of the associated clinical syndromes were phenotypically well circumscribed. ...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1002/ana.24200

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Annals of neurology
Volume:
76
Issue:
2
Pages:
168-184
Publication date:
2014-08-01
DOI:
EISSN:
1531-8249
ISSN:
0364-5134
Source identifiers:
470416
Language:
English
Pubs id:
pubs:470416
UUID:
uuid:550792b9-46b7-411f-afe6-5b6a458816dc
Local pid:
pubs:470416
Deposit date:
2014-07-04

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP