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Journal article

Nuclear iASPP may facilitate prostate cancer progression.

Abstract:

One of the major challenges in prostate cancer (PCa) research is the identification of key players that control the progression of primary cancers to invasive and metastatic disease. The majority of metastatic PCa express wild-type p53, whereas loss of p63 expression, a p53 family member, is a common event. Here we identify inhibitor of apoptosis-stimulating protein of p53 (iASPP), a common cellular regulator of p53 and p63, as an important player of PCa progression. Detailed analysis of the ...

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Publication status:
Published

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Publisher copy:
10.1038/cddis.2014.442

Authors


Morris, EV More by this author
Cerundolo, L More by this author
Verrill, C More by this author
Fritzsche, F More by this author
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Journal:
Cell death and disease
Volume:
5
Issue:
10
Pages:
e1492
Publication date:
2014
DOI:
EISSN:
2041-4889
ISSN:
2041-4889
URN:
uuid:5501c3b0-274a-42eb-9311-0b2a98fb3e7e
Source identifiers:
487433
Local pid:
pubs:487433
Language:
English

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