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Clinical and genetic correlates of growth differentiation factor 15 in the community.

Abstract:

BACKGROUND: Growth differentiation factor 15 (GDF15), a stress-responsive cytokine produced in cardiovascular cells under conditions of inflammation and oxidative stress, is emerging as an important prognostic marker in individuals with and without existing cardiovascular disease (CVD). We therefore examined the clinical and genetic correlates of circulating GDF15 concentrations, which have not been investigated collectively. METHODS: Plasma GDF15 concentrations were measured in 2991 particip...

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Publication status:
Published

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Authors


Mahajan, A More by this author
Larson, MG More by this author
McCabe, EL More by this author
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Journal:
Clinical chemistry
Volume:
58
Issue:
11
Pages:
1582-1591
Publication date:
2012-11-05
DOI:
EISSN:
1530-8561
ISSN:
0009-9147
URN:
uuid:54ef5651-af81-4b06-bfe0-577058f4ad84
Source identifiers:
352622
Local pid:
pubs:352622

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