Journal article icon

Journal article

A simple method to correct for the design effect in systematic reviews of trials using paired dichotomous data.

Abstract:

BACKGROUND AND OBJECTIVES: In systematic reviews of interventions of studies where randomization was done by individual but data are paired (such as eyes, ears), it is necessary to account for the natural clustering present. The Cochrane Handbook suggests treating these as examples of cluster randomized trials. An incorrect analysis (without adjustment) would usually overestimate the precision of the estimate. We discuss a simple method of adjustment that deals with this problem. METHODS: Fr...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences, Biomedical RC
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences, PHC-CTU
Role:
Author
Journal:
Journal of clinical epidemiology
Volume:
60
Issue:
9
Pages:
975-978
Publication date:
2007-09-05
DOI:
EISSN:
1878-5921
ISSN:
0895-4356
URN:
uuid:5492b6da-9264-4815-b189-5d5fdd23f592
Source identifiers:
116270
Local pid:
pubs:116270

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP