- Abstract:
- (Chemical Equation Presented) The terminators. A chain-termination approach was employed to rationally design monosaccharide derivatives as inhibitors of chitin biosynthesis by replacement of the 4-hydroxyl group of N-acetyl glucosamine monomers. Antifungal activity was observed for a variety of acylated monosaccharide and oxazoline derivatives by means of fungal-spore germination and adhesion assays. © 2007 Wiley-VCH Verlag GmbH and Co. KGaA.
- Publication status:
- Published
- Publisher copy:
- 10.1002/cbic.200700234
-
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- Journal:
- Chembiochem : a European journal of chemical biology
- Volume:
- 8
- Issue:
- 11
- Pages:
- 1241-1245
- Publication date:
- 2007-07-05
- DOI:
- EISSN:
-
1439-7633
- ISSN:
-
1439-4227
- URN:
-
uuid:5475ca6b-7501-4b3b-82eb-18b1f8ad1428
- Source identifiers:
-
33896
- Local pid:
- pubs:33896
- Language:
- English
- Keywords:
- Copyright date:
- 2007
Journal article
Carbohydrate chain terminators: rational design of novel carbohydrate-based antifungal agents.
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