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Journal article

Polymorphism in the serotonin transporter gene polymorphisms (5-HTTLPR) modifies the association between significant life events and depression in people with multiple sclerosis

Abstract:

Background:

In the general population, variation in the serotonin-transporter-linked polymorphic region (5-HTTLPR) has been shown to modify the association between stressful events and depression/anxiety. This has not been examined in people with multiple sclerosis (MS).

Objective:

We examined the interaction between significant life events (SLE), 5-HTTLPR and depression/anxiety.

Methods:

A population-bas...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1177/1352458518770021

Authors


Simpson, S More by this author
Ponsonby, A-L More by this author
Blizzard, L More by this author
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Publisher:
SAGE Publications Publisher's website
Journal:
Multiple Sclerosis Journal - Experimental, Translational and Clinical Journal website
Volume:
25
Issue:
6
Pages:
848-855
Publication date:
2018-04-23
Acceptance date:
2018-03-12
DOI:
ISSN:
2055-2173
Pubs id:
pubs:843974
URN:
uri:54741d70-77a1-4ea4-b41e-d4eeb2600e80
UUID:
uuid:54741d70-77a1-4ea4-b41e-d4eeb2600e80
Local pid:
pubs:843974

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