- Abstract:
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The influenza BM2 proton channel is a small, tetrameric α-helical membrane protein, which is vital in multiple stages of the life cycle of the virus. The transmembrane (TM) domain is responsible for modulating pH to facilitate release of viral genetic material whilst the cytoplasmic domain is purported to play a role in virus budding via interactions with another protein, BM1.
Coarse-grained molecular dynamics (CGMD) simulations have been employed in several studies of α-helical mem... Expand abstract - Files:
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Some thesis volumes scanned as part of the digitisation scheme funded by Dr Leonard Polonsky are currently unavailable due to sensitive material or uncleared third-party copyright content. We are attempting to contact authors whose theses are affected.
- Funding agency for:
- Sarah L Rouse
- Publication date:
- 2012
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Language:
- English
- Keywords:
- Subjects:
- Copyright holder:
- Sarah L Rouse
- Copyright date:
- 2011
Thesis
The influence of environment: simulations of the influenza BM2 proton channel
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+ Biotechnology and Biological Sciences Research Council
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