Thesis
The influence of environment: simulations of the influenza BM2 proton channel
- Abstract:
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The influenza BM2 proton channel is a small, tetrameric α-helical membrane protein, which is vital in multiple stages of the life cycle of the virus. The transmembrane (TM) domain is responsible for modulating pH to facilitate release of viral genetic material whilst the cytoplasmic domain is purported to play a role in virus budding via interactions with another protein, BM1.
Coarse-grained molecular dynamics (CGMD) simulations have been employed in several studies of α-helical mem... Expand abstract
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Funding
+ Biotechnology and Biological Sciences Research Council
More from this funder
Funding agency for:
Rouse, S
Bibliographic Details
- Publication date:
- 2012
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
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uuid:54427591-7c70-46dc-8f75-d7c991fbfc02
- Deposit date:
- 2016-11-15
Terms of use
- Copyright holder:
- Rouse, S
- Copyright date:
- 2011
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