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Preparation of liposomes incorporating membrane components from human lymphoid cells.

Abstract:

A procedure for the preparation of liposomes incorporating membrane components of human lymphoid cells is described, whereby the detergent used to solubilize the plasma membrane is almost completely eliminated. MHC products HLA-A-B-C and DR molecules were shown to be incorporated into the liposomes and their antigenic determinants to be exposed on the outer surface. A protein-rich liposomal fraction could be separated from both protein-free liposomes and from aggregates. This preparation may ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Tissue antigens
Volume:
14
Issue:
5
Pages:
385-397
Publication date:
1979-11-05
DOI:
EISSN:
1399-0039
ISSN:
0001-2815
URN:
uuid:54414c6a-0305-4f03-972a-2c953a7c3684
Source identifiers:
26543
Local pid:
pubs:26543

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