Journal article
Rapid progressing allele HLA-B35 Px restricted anti-HIV-1 CD8+ T cells recognize vestigial CTL epitopes.
- Abstract:
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BACKGROUND: The HLA-B*35-Px allele has been associated with rapid disease progression in HIV-1 infection, in contrast to the HLA-B*35-Py allele. METHODOLOGY/PRINCIPAL FINDINGS: Immune responses to two HLA-B*35 restricted HIV-1 specific CTL epitopes and their variants were followed longitudinally during early HIV-1 infection in 16 HLA-B*35+ individuals. Subjects expressing HLA-B*35-Px alleles showed no difference in response to the consensus epitopes compared to individuals with HLA-B*35-Py a...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 599.9KB)
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- Publisher copy:
- 10.1371/journal.pone.0010249
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Authors
Funding
University of California San Francisco (UCSF) AIDS Biology Program of the AIDS Research Institute (ARI)
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PloS one Journal website
- Volume:
- 5
- Issue:
- 4
- Article number:
- e10249
- Publication date:
- 2010-01-01
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
- Source identifiers:
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131203
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:5432b4dd-1fd6-4348-832d-6d402cac1fb9
- Local pid:
- pubs:131203
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Willberg et al
- Copyright date:
- 2010
- Notes:
- Copyright 2010 Willberg et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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