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Thesis

Genetic analyses of MAP kinase signalling in mouse gonad development

Abstract:

Sexual development begins with the process by which the bipotential gonads of the embryonic urogenital ridge develop into either testes or ovaries. In the mouse, sex determination occurs at around 11.5 dpc and depends on the presence or absence of the Y chromosome and the associated activity of the testis-determining gene, Sry, in supporting cell precursors. The mutually antagonistic male and female developmental pathways are regulated by many cellular and molecular processes, dis...

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Institution:
University of Oxford
Research group:
Mammalian Genetics Unit, Medical Research Council, Harwell
Oxford college:
Wolfson College
Department:
Medical Sciences Division - Biochemistry
Role:
Author

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Role:
Supervisor
Role:
Supervisor
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Funding agency for:
Rachel Joan Elizabeth Brixey
Publication date:
2011
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:54242de2-8e43-4cf2-ad12-d94a2c187c44
Local pid:
ora:8396

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