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Suction-induced basal cell cytolysis in the Weber-Cockayne variant of epidermolysis bullosa simplex.

Abstract:

In the Weber-Cockayne form of epidermolysis bullosa simplex (EBS-WC), trauma induces blisters which are confined to the palms and soles. Histologically, basal cell cytolysis is seen. We studied 6 patients with EBS-WC to determine the ultrastructural level at which artificially-induced suction blisters form. Blisters were raised by application of a suction blister cup to uninvolved forearm skin, the cup being connected to a negative pressure of 200 mm of mercury. The blisters were biopsied and...

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Publication status:
Published

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Authors


Venning, V More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Millard, PR More by this author
Journal:
Journal of cutaneous pathology
Volume:
20
Issue:
5
Pages:
389-392
Publication date:
1993-10-05
DOI:
EISSN:
1600-0560
ISSN:
0303-6987
URN:
uuid:540cdd14-0925-4024-bc36-3a9070c3234f
Source identifiers:
18080
Local pid:
pubs:18080

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