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Journal article

In vivo binding of [3H]nimodipine in rat brain after transient forebrain ischemia.

Abstract:

We report the regional variation in relative in vivo binding of the L-type voltage sensitive calcium channel (VSCC) antagonist [3H]nimodipine to brain following transient forebrain ischemia in the rat. At 30-min of reperfusion after 20 min of forebrain ischemia, [3H]nimodipine binding was significantly increased in striatum, CA3 and CA4, and dentate relative to binding in sham-operated rats, suggesting that VSCCs were responding to ischemic depolarization. Two h following ischemia, binding in...

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Publication status:
Published

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Publisher copy:
10.1038/jcbfm.1994.51

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Stroke and Geratology
Role:
Author
Journal:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Volume:
14
Issue:
3
Pages:
397-405
Publication date:
1994-05-01
DOI:
EISSN:
1559-7016
ISSN:
0271-678X
Source identifiers:
80186
Language:
English
Keywords:
Pubs id:
pubs:80186
UUID:
uuid:5386e961-7fad-4d60-bcf3-af4716636315
Local pid:
pubs:80186
Deposit date:
2012-12-19

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