- Abstract:
-
Cited1 is a transcriptional cofactor that interacts with Smad4, estrogen receptors α and β, TFAP2, and CBP/p300. It is expressed in a restricted manner in the embryo as well as in extraembryonic tissues during embryonic development. In this study we report the engineering of a loss-of-function Cited1 mutation in the mouse. Cited1 null mutants show growth restriction at 18.5 days postcoitum, and most of them die shortly after birth. Half the heterozygous females, i.e., those that carry a pater...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Publisher copy:
- 10.1128/MCB.24.1.228-244.2004
-
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- Publisher:
- American Society for Microbiology Publisher's website
- Journal:
- Molecular and Cellular Biology Journal website
- Volume:
- 24
- Issue:
- 1
- Pages:
- 228-244
- Publication date:
- 2004-01-01
- DOI:
- ISSN:
-
0270-7306
- URN:
-
uuid:537a38b3-4c83-4126-87ab-a86fbef07db0
- Source identifiers:
-
573471
- Local pid:
- pubs:573471
- Copyright holder:
- American Society for Microbiology
- Copyright date:
- 2004
Journal article
Cited1 is required in trophoblasts for placental development and for embryo growth and survival
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