Journal article
A brain-based pain facilitation mechanism contributes to painful diabetic polyneuropathy
- Abstract:
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The descending pain modulatory system represents one of the oldest and most fundamentally important neurophysiological mechanisms relevant to pain. Extensive work in animals and humans has shown how a functional imbalance between the facilitatory and inhibitory components is linked to exacerbation and maintenance of persistent pain states. Forward translation of these findings into clinical populations is needed to verify the relevance of this imbalance. Diabetic polyneuropathy is one of the ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, 821.0KB)
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- Publisher copy:
- 10.1093/brain/awx337
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Authors
Funding
National Institute for Health Research
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Medical Research Council
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Wellcome Trust
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Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Brain Journal website
- Volume:
- 141
- Issue:
- 2
- Pages:
- 357-364
- Publication date:
- 2018-01-15
- Acceptance date:
- 2017-10-19
- DOI:
- EISSN:
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1460-2156
- ISSN:
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0006-8950
- Pmid:
-
29346515
- Source identifiers:
-
821023
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:821023
- UUID:
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uuid:53772324-8f21-4c53-9ef6-be95e975999c
- Local pid:
- pubs:821023
- Deposit date:
- 2018-02-06
Terms of use
- Copyright holder:
- Segerdahl et al
- Copyright date:
- 2018
- Rights statement:
- Copyright © 2018 The Authors. Published by Oxford University Press on behalf of the Guarantors of Brain. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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