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Preparation, characterization, and release of amoxicillin from electrospun fibrous wound dressing patches.

Abstract:

PURPOSE: To produce electrospun polymeric fibrous wound dressing patches that can release the antibiotic drug amoxicillin in a controlled manner. METHODS: Poly(D,L-lactide-co-glycolide) acid (PLGA) fibrous dressings with entrapped amoxicillin were produced by electrospinning. The morphology and successful entrapment of amoxicillin in the PLGA fibrous dressings were validated by scanning electron microscopy (SEM) and Fourier Transform Infrared (FTIR) spectroscopy. The rate of drug release fro...

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Publication status:
Published

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Publisher copy:
10.1007/s11095-013-1035-2

Authors


Journal:
Pharmaceutical research
Volume:
30
Issue:
7
Pages:
1926-1938
Publication date:
2013-07-01
DOI:
EISSN:
1573-904X
ISSN:
0724-8741
Source identifiers:
402226
Language:
English
Keywords:
Pubs id:
pubs:402226
UUID:
uuid:536fa626-7337-49a3-8d82-3eb5cbae83c9
Local pid:
pubs:402226
Deposit date:
2013-11-16

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