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TLDc proteins: new players in the oxidative stress response and neurological disease

Abstract:

Oxidative stress (OS) arises from an imbalance in the cellular redox state, which can lead to intracellular damage and ultimately cell death. OS occurs as a result of normal ageing, but it is also implicated as a common etiological factor in neurological disease; thus identifying novel proteins that modulate the OS response may facilitate the design of new therapeutic approaches applicable to many disorders. In this review, we describe the recent progress that has been made using a range of g...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1007/s00335-017-9706-7

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Publisher:
Springer Verlag Publisher's website
Journal:
Mammalian Genome Journal website
Volume:
28
Issue:
9-10
Pages:
395-406
Publication date:
2017-07-13
Acceptance date:
2017-07-03
DOI:
EISSN:
1432-1777
ISSN:
0938-8990
Pubs id:
pubs:709100
URN:
uri:53656ab8-3544-478b-ab75-a7a419d051e5
UUID:
uuid:53656ab8-3544-478b-ab75-a7a419d051e5
Local pid:
pubs:709100
Language:
English
Keywords:

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