- Abstract:
-
Background T-cell responses against highly conserved influenza antigens have been previously associated with protection. However, these immune responses are poorly maintained following recovery from influenza infection and are not boosted by inactivated influenza vaccines. We have previously demonstrated the safety and immunogenicity of two viral vectored vaccines, modified vaccinia virus Ankara (MVA) and the chimpanzee adenovirus ChAdOx1 expressing conserved influenza virus ... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 181.1kb)
-
(pdf, 855.3kb)
-
- Publisher copy:
- 10.1016/j.ebiom.2018.02.011
-
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- Publisher:
- Elsevier Publisher's website
- Journal:
- EBioMedicine Journal website
- Volume:
- 29
- Pages:
- 146-154
- Publication date:
- 2018-02-15
- Acceptance date:
- 2018-02-13
- DOI:
- ISSN:
-
2352-3964
- Pubs id:
-
pubs:825876
- URN:
-
uri:5360e7ba-ace2-4886-b57b-f8e8acb45025
- UUID:
-
uuid:5360e7ba-ace2-4886-b57b-f8e8acb45025
- Local pid:
- pubs:825876
- Copyright holder:
- Coughlan et al.
- Copyright date:
- 2018
- Notes:
- Copyright © 2018 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license(http://creativecommons. org/licenses/by/4.0/)
Journal article
Heterologous two-dose vaccination with simian adenovirus and poxvirus vectors elicits long-lasting cellular immunity to influenza virus A in healthy adults
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