Journal article
Heterologous two-dose vaccination with simian adenovirus and poxvirus vectors elicits long-lasting cellular immunity to influenza virus A in healthy adults
- Abstract:
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Background T-cell responses against highly conserved influenza antigens have been previously associated with protection. However, these immune responses are poorly maintained following recovery from influenza infection and are not boosted by inactivated influenza vaccines. We have previously demonstrated the safety and immunogenicity of two viral vectored vaccines, modified vaccinia virus Ankara (MVA) and the chimpanzee adenovirus ChAdOx1 expressing conserved influenza virus ... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 181.1KB)
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(Version of record, pdf, 855.3KB)
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- Publisher copy:
- 10.1016/j.ebiom.2018.02.011
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Authors
Funding
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- EBioMedicine Journal website
- Volume:
- 29
- Pages:
- 146-154
- Publication date:
- 2018-02-15
- Acceptance date:
- 2018-02-13
- DOI:
- ISSN:
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2352-3964
- Source identifiers:
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825876
Item Description
- Keywords:
- Pubs id:
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pubs:825876
- UUID:
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uuid:5360e7ba-ace2-4886-b57b-f8e8acb45025
- Local pid:
- pubs:825876
- Deposit date:
- 2018-02-22
Terms of use
- Copyright holder:
- Coughlan et al
- Copyright date:
- 2018
- Notes:
- Copyright © 2018 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license(http://creativecommons. org/licenses/by/4.0/)
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