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Determining the pneumococcal conjugate vaccine coverage required for indirect protection against vaccine-type pneumococcal carriage in low and middle-income countries: a protocol for a prospective observational study

Abstract:

Pneumococcal conjugate vaccines (PCVs) prevent disease through both direct protection of vaccinated individuals and indirect protection of unvaccinated individuals by reducing nasopharyngeal (NP) carriage and transmission of vaccine-type (VT) pneumococci. While the indirect effects of PCV vaccination are well described, the PCV coverage required to achieve the indirect effects is unknown. We will investigate the relationship between PCV coverage and VT carriage among undervaccinated children ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1136/bmjopen-2018-021512

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ORCID:
0000-0002-8536-2048
Nguyen, CD More by this author
Andrews, R More by this author
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Publisher:
BMJ Publishing Group Publisher's website
Journal:
BMJ Open Journal website
Volume:
8
Issue:
5
Pages:
Article: e021512
Publication date:
2018-05-18
Acceptance date:
2018-04-25
DOI:
ISSN:
2044-6055
Pubs id:
pubs:852955
URN:
uri:534d7d7d-4353-44d2-b527-d1f830051205
UUID:
uuid:534d7d7d-4353-44d2-b527-d1f830051205
Local pid:
pubs:852955
Language:
English

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