- Abstract:
-
The human genome is often portrayed as consisting of three sequence types, each distinguished by their mode of evolution. Purifying selection is estimated to act on 2.5-5.0% of the genome, whereas virtually all remaining sequence is considered to have evolved neutrally and to be devoid of functionality. The third mode of evolution, positive selection of advantageous changes, is considered rare. Such instances have been inferred only for a handful of sites, and these lie almost exclusively wit...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1093/hmg/ddl182
-
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- Journal:
- Human molecular genetics
- Volume:
- 15 Spec No 2
- Issue:
- SUPPL. 2
- Pages:
- R170-R175
- Publication date:
- 2006-10-05
- DOI:
- EISSN:
-
1460-2083
- ISSN:
-
0964-6906
- URN:
-
uuid:531a6d84-7125-48fd-85e3-a5f38a492b41
- Source identifiers:
-
68187
- Local pid:
- pubs:68187
- Language:
- English
- Keywords:
- Copyright date:
- 2006
Journal article
Signatures of adaptive evolution within human non-coding sequence.
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