Journal article
Signatures of adaptive evolution within human non-coding sequence.
- Abstract:
-
The human genome is often portrayed as consisting of three sequence types, each distinguished by their mode of evolution. Purifying selection is estimated to act on 2.5-5.0% of the genome, whereas virtually all remaining sequence is considered to have evolved neutrally and to be devoid of functionality. The third mode of evolution, positive selection of advantageous changes, is considered rare. Such instances have been inferred only for a handful of sites, and these lie almost exclusively wit...
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- Publication status:
- Published
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- Publisher copy:
- 10.1093/hmg/ddl182
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Bibliographic Details
- Journal:
- Human molecular genetics
- Volume:
- 15 Spec No 2
- Issue:
- SUPPL. 2
- Pages:
- R170-R175
- Publication date:
- 2006-10-01
- DOI:
- EISSN:
-
1460-2083
- ISSN:
-
0964-6906
- Source identifiers:
-
68187
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:68187
- UUID:
-
uuid:531a6d84-7125-48fd-85e3-a5f38a492b41
- Local pid:
- pubs:68187
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2006
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