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Journal article

Implications of HIV diversity for the HIV-1 pandemic.

Abstract:

HIV-1 genetic variability within individuals and populations plays a central role in the HIV pandemic. Multiple zoonotic transmissions of SIV to humans have resulted in distinct HIV lineages in humans which have further diversified within the population over time. High rates of mutation and recombination during HIV reverse transcription create a genetic diversity in the host which is subject to selection pressures by the immune response and antiretroviral treatment. The global distribution of...

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Publication status:
Published

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Publisher copy:
10.1016/j.jinf.2012.10.026

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Institution:
University of Oxford
Department:
Oxford, MSD, Obstetrics and Gynaecology
Role:
Author
Journal:
The Journal of infection
Volume:
66
Issue:
5
Pages:
391-400
Publication date:
2013-05-05
DOI:
EISSN:
1532-2742
ISSN:
0163-4453
URN:
uuid:53114a6d-8612-4824-b103-1f359dea4ad0
Source identifiers:
374531
Local pid:
pubs:374531
Language:
English
Keywords:

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