- Abstract:
-
HIV-1 genetic variability within individuals and populations plays a central role in the HIV pandemic. Multiple zoonotic transmissions of SIV to humans have resulted in distinct HIV lineages in humans which have further diversified within the population over time. High rates of mutation and recombination during HIV reverse transcription create a genetic diversity in the host which is subject to selection pressures by the immune response and antiretroviral treatment. The global distribution of...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.jinf.2012.10.026
-
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- Journal:
- The Journal of infection
- Volume:
- 66
- Issue:
- 5
- Pages:
- 391-400
- Publication date:
- 2013-05-05
- DOI:
- EISSN:
-
1532-2742
- ISSN:
-
0163-4453
- URN:
-
uuid:53114a6d-8612-4824-b103-1f359dea4ad0
- Source identifiers:
-
374531
- Local pid:
- pubs:374531
- Language:
- English
- Keywords:
- Copyright date:
- 2013
Journal article
Implications of HIV diversity for the HIV-1 pandemic.
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