Journal article
Lineage structure of Streptococcus pneumoniae may be driven by immune selection on the groEL heat-shock protein
- Abstract:
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Populations of Streptococcus pneumoniae (SP) are typically structured into groups of closely related organisms or lineages, but it is not clear whether they are maintained by selection or neutral processes. Here, we attempt to address this question by applying a machine learning technique to SP whole genomes. Our results indicate that lineages evolved through immune selection on the groEL chaperone protein. The groEL protein is part of the groESL operon and enables a large range of proteins t...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.8MB)
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- Publisher copy:
- 10.1038/s41598-017-08990-z
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Authors
Funding
Bibliographic Details
- Publisher:
- Springer Nature Publisher's website
- Journal:
- Scientific Reports Journal website
- Volume:
- 7
- Pages:
- 9023
- Publication date:
- 2017-08-22
- Acceptance date:
- 2017-07-11
- DOI:
- EISSN:
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2045-2322
- ISSN:
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2045-2322
Item Description
- Pubs id:
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pubs:718278
- UUID:
-
uuid:52e4b57b-8bfc-43bd-acae-995cc1d5c069
- Local pid:
- pubs:718278
- Deposit date:
- 2017-08-16
Terms of use
- Copyright holder:
- Lourenço et al
- Copyright date:
- 2017
- Notes:
- © The Author(s) 2017. This work is licensed under a Creative Commons Attribution 4.0 International License.
- Licence:
- CC Attribution (CC BY)
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