- Abstract:
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Populations of Streptococcus pneumoniae (SP) are typically structured into groups of closely related organisms or lineages, but it is not clear whether they are maintained by selection or neutral processes. Here, we attempt to address this question by applying a machine learning technique to SP whole genomes. Our results indicate that lineages evolved through immune selection on the groEL chaperone protein. The groEL protein is part of the groESL operon and enables a large range of proteins t...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
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(pdf, 1.8MB)
-
- Publisher copy:
- 10.1038/s41598-017-08990-z
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- Publisher:
- Springer Nature Publisher's website
- Journal:
- Scientific Reports Journal website
- Volume:
- 7
- Pages:
- 9023
- Publication date:
- 2017-08-22
- Acceptance date:
- 2017-07-11
- DOI:
- EISSN:
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2045-2322
- ISSN:
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2045-2322
- Pubs id:
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pubs:718278
- URN:
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uri:52e4b57b-8bfc-43bd-acae-995cc1d5c069
- UUID:
-
uuid:52e4b57b-8bfc-43bd-acae-995cc1d5c069
- Local pid:
- pubs:718278
- Copyright holder:
- Lourenço et al.
- Copyright date:
- 2017
- Notes:
- © The Author(s) 2017. This work is licensed under a Creative Commons Attribution 4.0 International License.
Journal article
Lineage structure of Streptococcus pneumoniae may be driven by immune selection on the groEL heat-shock protein
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